“The Cannabinoid Receptors”
نویسنده
چکیده
As research has progressed, the cannabinoid CB1 and CB2 receptors have expanded significantly in importance within the neuroscience mainstream. In the presented book leading experts introduce newcomers to the cannabinoid field with chapters covering cannabinoid ligand synthesis and structure activity relationships, the molecular pharmacology of the cannabinoid receptors and the endocannabinoid system, and ultimately, the whole animal pharmacology and therapeutic applications for cannabinoid drugs, what is of particular pharmaceutical interest. Adding to those key topics, the book also examines the current direction of the field with chapters on new putative cannabinoid receptors and challenges for future research. As a part of "The Receptors" series (edited by Kim A. Neve), this volume highlights the cannabinoid receptors with the most thorough, focused and essential information available. Comprehensive and cutting-edge, "The Cannabinoid Receptors" serves as ideal guidebook for Pharmacologists, molecular biologists and neurobiologists covering this fascinating and vital field in a thorough and focused manner.
منابع مشابه
Involvement of α-1-adrenergic receptors in central region of amygdala and the effects of cannabinoid agonist on inhibitory avoidance memory in male rats
Introduction: There are many similarities between memory impairment in patients suffering from Alzheimer and animals treated by Cannabinoids. The agonists of Cannabinoid receptors affect on a variety of memories and leanings. The present study aims to investigate the role of α-1-adrenergic receptors in central region of amygdala in state-dependent learning induced by WIN55,212-2 (cannabin...
متن کاملInteraction between cannabinoid receptors and inhibition of L-type calcium channel on passive avoidance learning and memory in male rats
Introduction: There is currently a debate over the interaction between Ca2+ channels and cannabinoid system on learning and memory processing. In this study, we examined the effect of acute injection of cannabinoid agonist (Win- 55212-2) (Win) or antagonist (AM251), following chronic injection of verapamil, as a L-type Ca2+ channels blocker, on passive avoidance (PA) test in male Wistar rats...
متن کاملChemical Cannabis; the New Trend of Addiction in Iran
Synthetic cannabinoids (SC) are a heterogeneous group of substances with a high affinity for cannabinoid receptors. Unlike Δ9-tetrahydrocannabinol (THC), synthetic cannabinoids are incredibly potent, highly productive, have more affinity for the Cannabinoid receptor type 1 (CB1), and Cannabinoid receptor type 2 (CB2), and are designed to accelerate the effects of tetrahydrocannabinol. Also, the...
متن کاملCannabinoid CB1 Receptors Mediate the Gastroprotective Effect of Neurotensin
Objective(s) Several lines of evidence indicate that neuropeptides exhibit protective properties against gastroduodenal ulcers. Neurotensin, a gut-brain neuropeptide, is implicated in a number of physiological processes in the central nervous system and peripheral tissues including gastrointestinal tract. In the present study, we aimed to investigate the gastroprotective potential of either p...
متن کاملCB1 cannabinoid receptors are involved in neuroleptic-induced enhancement of brain neurotensin
Objective(s): Targeting the neuropeptide systems has been shown to be useful for the development of more effective antipsychotic drugs. Neurotensin, an endogenous neuropeptide, appears to be involved in the mechanism of action of antipsychotics. However, the available data provide conflicting results and the mechanism(s) by which antipsychotics affect brain neurotensin neurotransmission have no...
متن کاملنقش گیرندههای محیطی گلیسین در اخذ غذای وابسته به گیرندههای کانابینوئیدی
Background & Aim: Peripheral cannabinoid and glycine receptors are involved in food intake regulation. This study was conducted to investigate the possible interaction between these two receptors in regulating food intake. Methods: This is an experimental study which was conducted on forty male Wistar rats. In the first phase of the experiment, the rats simultaneously received intraperitonea...
متن کامل